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Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans

BACKGROUND: Iron is a key pathogenic determinant of many infectious diseases. Hepcidin, the hormone responsible for governing systemic iron homeostasis, is widely hypothesized to represent a key component of nutritional immunity through regulating the accessibility of iron to invading microorganisms...

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Detalles Bibliográficos
Autores principales:	Darton, Thomas C., Blohmke, Christoph J., Giannoulatou, Eleni, Waddington, Claire S., Jones, Claire, Sturges, Pamela, Webster, Craig, Drakesmith, Hal, Pollard, Andrew J., Armitage, Andrew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578949/ https://www.ncbi.nlm.nih.gov/pubmed/26394303 http://dx.doi.org/10.1371/journal.pntd.0004029

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