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Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up

Recent findings indicate that microglia in Alzheimer’s disease (AD) is senescent whereas peripheral blood mononuclear cells (PBMCs) could infiltrate the brain to phagocyte amyloid deposits. However, the molecular mechanisms involved in the amyloid peptide clearance remain unknown. Autophagy is a phy...

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Detalles Bibliográficos
Autores principales:	François, Arnaud, Julian, Adrien, Ragot, Stéphanie, Dugast, Emilie, Blanchard, Ludovic, Brishoual, Sonia, Chassaing, Damien, Page, Guylène, Paccalin, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578953/ https://www.ncbi.nlm.nih.gov/pubmed/26393801 http://dx.doi.org/10.1371/journal.pone.0138326

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