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A Novel Bmal1 Mutant Mouse Reveals Essential Roles of the C-Terminal Domain on Circadian Rhythms

The mammalian circadian clock is an endogenous biological timer comprised of transcriptional/translational feedback loops of clock genes. Bmal1 encodes an indispensable transcription factor for the generation of circadian rhythms. Here, we report a new circadian mutant mouse from gene-trapped embryo...

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Detalles Bibliográficos
Autores principales: Park, Noheon, Kim, Hee-Dae, Cheon, Solmi, Row, Hansang, Lee, Jiyeon, Han, Dong-Hee, Cho, Sehyung, Kim, Kyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578957/
https://www.ncbi.nlm.nih.gov/pubmed/26394143
http://dx.doi.org/10.1371/journal.pone.0138661

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