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A Novel Bmal1 Mutant Mouse Reveals Essential Roles of the C-Terminal Domain on Circadian Rhythms
The mammalian circadian clock is an endogenous biological timer comprised of transcriptional/translational feedback loops of clock genes. Bmal1 encodes an indispensable transcription factor for the generation of circadian rhythms. Here, we report a new circadian mutant mouse from gene-trapped embryo...
Autores principales: | Park, Noheon, Kim, Hee-Dae, Cheon, Solmi, Row, Hansang, Lee, Jiyeon, Han, Dong-Hee, Cho, Sehyung, Kim, Kyungjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578957/ https://www.ncbi.nlm.nih.gov/pubmed/26394143 http://dx.doi.org/10.1371/journal.pone.0138661 |
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