Neonatal vaginal irritation results in long-term visceral and somatic hypersensitivity and increased hypothalamic–pituitary–adrenal axis output in female mice

Experiencing early life stress or injury increases a woman's likelihood of developing vulvodynia and concomitant dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis. To investigate the outcome of neonatal vaginal irritation (NVI), female mouse pups were administered intravaginal zymo...

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Detalles Bibliográficos
Autores principales: Pierce, Angela N., Zhang, Zhen, Fuentes, Isabella M., Wang, Ruipeng, Ryals, Janelle M., Christianson, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578984/
https://www.ncbi.nlm.nih.gov/pubmed/26098441
http://dx.doi.org/10.1097/j.pain.0000000000000264

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