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Reassembly and co-crystallization of a family 9 processive endoglucanase from its component parts: structural and functional significance of the intermodular linker

Non-cellulosomal processive endoglucanase 9I (Cel9I) from Clostridium thermocellum is a modular protein, consisting of a family-9 glycoside hydrolase (GH9) catalytic module and two family-3 carbohydrate-binding modules (CBM3c and CBM3b), separated by linker regions. GH9 does not show cellulase activ...

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Detalles Bibliográficos
Autores principales: Petkun, Svetlana, Rozman Grinberg, Inna, Lamed, Raphael, Jindou, Sadanari, Burstein, Tal, Yaniv, Oren, Shoham, Yuval, Shimon, Linda J.W., Bayer, Edward A., Frolow, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579020/
https://www.ncbi.nlm.nih.gov/pubmed/26401442
http://dx.doi.org/10.7717/peerj.1126