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Local Delivery of High-Dose Chondroitinase ABC in the Sub-Acute Stage Promotes Axonal Outgrowth and Functional Recovery after Complete Spinal Cord Transection

Chondroitin sulfate proteoglycans (CSPGs) are glial scar-associated molecules considered axonal regeneration inhibitors and can be digested by chondroitinase ABC (ChABC) to promote axonal regeneration after spinal cord injury (SCI). We previously demonstrated that intrathecal delivery of low-dose Ch...

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Detalles Bibliográficos
Autores principales:	Cheng, Chu-Hsun, Lin, Chi-Te, Lee, Meng-Jen, Tsai, May-Jywan, Huang, Wen-Hung, Huang, Ming-Chao, Lin, Yi-Lo, Chen, Ching-Jung, Huang, Wen-Cheng, Cheng, Henrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579094/ https://www.ncbi.nlm.nih.gov/pubmed/26393921 http://dx.doi.org/10.1371/journal.pone.0138705

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