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Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice

The fractalkine (CX3CL1-CX3CR1) chemokine system is associated with obesity-related inflammation and type 2 diabetes, but data on effects of Cx3cr1 deficiency on metabolic pathways is contradictory. We examined male C57BL/6 Cx3cr1(-/-) mice on chow and high-fat diet to determine the metabolic effect...

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Detalles Bibliográficos
Autores principales:	Shah, Rachana, O’Neill, Sean M., Hinkle, Christine, Caughey, Jennifer, Stephan, Stephen, Lynch, Emma, Bermingham, Kate, Lynch, Gina, Ahima, Rexford S., Reilly, Muredach P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579121/ https://www.ncbi.nlm.nih.gov/pubmed/26393344 http://dx.doi.org/10.1371/journal.pone.0138317

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