Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

The VAR2CSA protein of Plasmodium falciparum is transported to and expressed on the infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the current leading candidate for a vaccine to prevent PM. However, the antigenic polymorphism integral to VAR2CSA poses a chall...

Descripción completa

Detalles Bibliográficos
Autores principales: Doritchamou, Justin, Sabbagh, Audrey, Jespersen, Jakob S., Renard, Emmanuelle, Salanti, Ali, Nielsen, Morten A., Deloron, Philippe, Tuikue Ndam, Nicaise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579133/
https://www.ncbi.nlm.nih.gov/pubmed/26393516
http://dx.doi.org/10.1371/journal.pone.0137695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579133/
https://www.ncbi.nlm.nih.gov/pubmed/26393516
http://dx.doi.org/10.1371/journal.pone.0137695

Ejemplares similares