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Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

The VAR2CSA protein of Plasmodium falciparum is transported to and expressed on the infected erythrocyte surface where it plays a key role in placental malaria (PM). It is the current leading candidate for a vaccine to prevent PM. However, the antigenic polymorphism integral to VAR2CSA poses a chall...

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Detalles Bibliográficos
Autores principales:	Doritchamou, Justin, Sabbagh, Audrey, Jespersen, Jakob S., Renard, Emmanuelle, Salanti, Ali, Nielsen, Morten A., Deloron, Philippe, Tuikue Ndam, Nicaise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579133/ https://www.ncbi.nlm.nih.gov/pubmed/26393516 http://dx.doi.org/10.1371/journal.pone.0137695

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