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A constraint-based modelling approach to metabolic dysfunction in Parkinson's disease

One of the hallmarks of sporadic Parkinson's disease is degeneration of dopaminergic neurons in the pars compacta of the substantia nigra. The aetiopathogenesis of this degeneration is still not fully understood, with dysfunction of many biochemical pathways in different subsystems suggested to...

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Detalles Bibliográficos
Autores principales:	Mao, Longfei, Nicolae, Averina, Oliveira, Miguel A.P., He, Feng, Hachi, Siham, Fleming, Ronan M.T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2015
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579274/ https://www.ncbi.nlm.nih.gov/pubmed/26504511 http://dx.doi.org/10.1016/j.csbj.2015.08.002

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