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Postoperative Autologous Reinfusion in Total Knee Replacement
Surgeries for total knee replacement (TKR) are increasing and in this context there is a need to develop new protocols for management and use of blood transfusion therapy. Autologous blood reduces the need for allogeneic blood transfusion and the aim of the present study was to verify the safety and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579317/ https://www.ncbi.nlm.nih.gov/pubmed/26442168 http://dx.doi.org/10.1155/2015/826790 |
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author | Crescibene, A. Martire, F. Gigliotti, P. Rende, A. Candela, M. |
author_facet | Crescibene, A. Martire, F. Gigliotti, P. Rende, A. Candela, M. |
author_sort | Crescibene, A. |
collection | PubMed |
description | Surgeries for total knee replacement (TKR) are increasing and in this context there is a need to develop new protocols for management and use of blood transfusion therapy. Autologous blood reduces the need for allogeneic blood transfusion and the aim of the present study was to verify the safety and the clinical efficacy. An observational retrospective study has been conducted on 124 patients, undergoing cemented total knee prosthesis replacement. Observed population was stratified into two groups: the first group received reinfusion of autologous blood collected in the postoperative surgery and the second group did not receive autologous blood reinfusion. Analysis of data shows that patients undergoing autologous blood reinfusion received less homologous blood bags (10.6% versus 30%; p = 0.08) and reduced days of hospitalization (7.88 ± 0.7 days versus 8.96 ± 2.47 days for the control group; p = 0.03). Microbiological tests were negative in all postoperatively salvaged and reinfused units. Our results emphasize the effectiveness of this procedure and have the characteristics of simplicity, low cost (€97.53 versus €103.79; p < 0.01), and easy reproducibility. Use of autologous drainage system postoperatively is a procedure that allows reducing transfusion of homologous blood bags in patients undergoing TKR. |
format | Online Article Text |
id | pubmed-4579317 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-45793172015-10-05 Postoperative Autologous Reinfusion in Total Knee Replacement Crescibene, A. Martire, F. Gigliotti, P. Rende, A. Candela, M. J Blood Transfus Clinical Study Surgeries for total knee replacement (TKR) are increasing and in this context there is a need to develop new protocols for management and use of blood transfusion therapy. Autologous blood reduces the need for allogeneic blood transfusion and the aim of the present study was to verify the safety and the clinical efficacy. An observational retrospective study has been conducted on 124 patients, undergoing cemented total knee prosthesis replacement. Observed population was stratified into two groups: the first group received reinfusion of autologous blood collected in the postoperative surgery and the second group did not receive autologous blood reinfusion. Analysis of data shows that patients undergoing autologous blood reinfusion received less homologous blood bags (10.6% versus 30%; p = 0.08) and reduced days of hospitalization (7.88 ± 0.7 days versus 8.96 ± 2.47 days for the control group; p = 0.03). Microbiological tests were negative in all postoperatively salvaged and reinfused units. Our results emphasize the effectiveness of this procedure and have the characteristics of simplicity, low cost (€97.53 versus €103.79; p < 0.01), and easy reproducibility. Use of autologous drainage system postoperatively is a procedure that allows reducing transfusion of homologous blood bags in patients undergoing TKR. Hindawi Publishing Corporation 2015 2015-09-09 /pmc/articles/PMC4579317/ /pubmed/26442168 http://dx.doi.org/10.1155/2015/826790 Text en Copyright © 2015 A. Crescibene et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Crescibene, A. Martire, F. Gigliotti, P. Rende, A. Candela, M. Postoperative Autologous Reinfusion in Total Knee Replacement |
title | Postoperative Autologous Reinfusion in Total Knee Replacement |
title_full | Postoperative Autologous Reinfusion in Total Knee Replacement |
title_fullStr | Postoperative Autologous Reinfusion in Total Knee Replacement |
title_full_unstemmed | Postoperative Autologous Reinfusion in Total Knee Replacement |
title_short | Postoperative Autologous Reinfusion in Total Knee Replacement |
title_sort | postoperative autologous reinfusion in total knee replacement |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579317/ https://www.ncbi.nlm.nih.gov/pubmed/26442168 http://dx.doi.org/10.1155/2015/826790 |
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