Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer

Sporadic breast cancer (SBC) is a common disease without robust means of early risk prediction in the population. We studied 282 females with SBC, focusing on copy number aberrations in cancer-free breast tissue (uninvolved margin, UM) outside the primary tumor (PT). In total, 1162 UMs (1–14 per bre...

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Detalles Bibliográficos
Autores principales: Forsberg, Lars A., Rasi, Chiara, Pekar, Gyula, Davies, Hanna, Piotrowski, Arkadiusz, Absher, Devin, Razzaghian, Hamid Reza, Ambicka, Aleksandra, Halaszka, Krzysztof, Przewoźnik, Marcin, Kruczak, Anna, Mandava, Geeta, Pasupulati, Saichand, Hacker, Julia, Prakash, K. Reddy, Dasari, Ravi Chandra, Lau, Joey, Penagos-Tafurt, Nelly, Olofsson, Helena M., Hallberg, Gunilla, Skotnicki, Piotr, Mituś, Jerzy, Skokowski, Jaroslaw, Jankowski, Michal, Śrutek, Ewa, Zegarski, Wojciech, Tiensuu Janson, Eva, Ryś, Janusz, Tot, Tibor, Dumanski, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579338/
https://www.ncbi.nlm.nih.gov/pubmed/26430163
http://dx.doi.org/10.1101/gr.187823.114

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