The frequent evolutionary birth and death of functional promoters in mouse and human

Promoters are central to the regulation of gene expression. Changes in gene regulation are thought to underlie much of the adaptive diversification between species and phenotypic variation within populations. In contrast to earlier work emphasizing the importance of enhancer evolution and subtle seq...

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Detalles Bibliográficos
Autores principales: Young, Robert S., Hayashizaki, Yoshihide, Andersson, Robin, Sandelin, Albin, Kawaji, Hideya, Itoh, Masayoshi, Lassmann, Timo, Carninci, Piero, Bickmore, Wendy A., Forrest, Alistair R., Taylor, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579340/
https://www.ncbi.nlm.nih.gov/pubmed/26228054
http://dx.doi.org/10.1101/gr.190546.115

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