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Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism

Antidepressants often disrupt sleep. Vortioxetine, a multimodal antidepressant acting through serotonin (5-HT) transporter (SERT) inhibition, 5-HT(3), 5-HT(7) and 5-HT(1D) receptor antagonism, 5-HT(1B) receptor partial agonism, and 5-HT(1A) receptor agonism, had fewer incidences of sleep-related adv...

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Detalles Bibliográficos
Autores principales:	Leiser, Steven C, Iglesias-Bregna, Deborah, Westrich, Ligia, Pehrson, Alan L, Sanchez, Connie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2015
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579402/ https://www.ncbi.nlm.nih.gov/pubmed/26174134 http://dx.doi.org/10.1177/0269881115592347

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