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Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules

Cytoplasmic dynein is a dimeric AAA(+) motor protein that performs critical roles in eukaryotic cells by moving along microtubules using ATP. Here using cryo-electron microscopy we directly observe the structure of Dictyostelium discoideum dynein dimers on microtubules at near-physiological ATP conc...

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Detalles Bibliográficos
Autores principales:	Imai, Hiroshi, Shima, Tomohiro, Sutoh, Kazuo, Walker, Matthew L., Knight, Peter J., Kon, Takahide, Burgess, Stan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579568/ https://www.ncbi.nlm.nih.gov/pubmed/26365535 http://dx.doi.org/10.1038/ncomms9179

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