Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling

Defective hepatic insulin receptor (IR) signalling is a pathogenic manifestation of metabolic disorders including obesity and diabetes. The endo/lysosomal trafficking system may coordinate insulin action and nutrient homeostasis by endocytosis of IR and the autophagic control of intracellular nutrie...

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Detalles Bibliográficos
Autores principales: Nemazanyy, Ivan, Montagnac, Guillaume, Russell, Ryan C., Morzyglod, Lucille, Burnol, Anne-Françoise, Guan, Kun-Liang, Pende, Mario, Panasyuk, Ganna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579570/
https://www.ncbi.nlm.nih.gov/pubmed/26387534
http://dx.doi.org/10.1038/ncomms9283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579570/
https://www.ncbi.nlm.nih.gov/pubmed/26387534
http://dx.doi.org/10.1038/ncomms9283

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