Secreted frizzled-related protein promotors are hypermethylated in cutaneous squamous carcinoma compared with normal epidermis

BACKGROUND: The Wnt signaling pathway is abnormally activated in many human cancers. Secreted frizzled-related proteins (SFRPs) function as negative regulators of Wnt signaling and play an important role in carcinogenesis. SFRP promoter hypermethylation has often been identified in human cancers; ho...

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Detalles Bibliográficos
Autores principales: Liang, Junqin, Kang, Xiaojing, Halifu, Yilinuer, Zeng, Xuewen, Jin, Tianbo, Zhang, Mingxia, Luo, Dong, Ding, Yuan, Zhou, Yunmin, Yakeya, Buwajier, Abudu, Dilinuer, Pu, Xiongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579584/
https://www.ncbi.nlm.nih.gov/pubmed/26394929
http://dx.doi.org/10.1186/s12885-015-1650-x

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