Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy

Dimercaptosuccinic acid (DMSA) is an analog of dimercaprol used as metal chelating moiety in variety of conditions. In nuclear medicine itself two types of Tc-99m DMSA complexes are used, trivalent and pentavalent forms. In this review, we have discussed the mechanism of uptake of both complexes as...

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Detalles Bibliográficos
Autores principales: Shukla, Jaya, Mittal, Bhagwant Rai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579612/
https://www.ncbi.nlm.nih.gov/pubmed/26430311
http://dx.doi.org/10.4103/0972-3919.164015
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author Shukla, Jaya
Mittal, Bhagwant Rai
author_facet Shukla, Jaya
Mittal, Bhagwant Rai
author_sort Shukla, Jaya
collection PubMed
description Dimercaptosuccinic acid (DMSA) is an analog of dimercaprol used as metal chelating moiety in variety of conditions. In nuclear medicine itself two types of Tc-99m DMSA complexes are used, trivalent and pentavalent forms. In this review, we have discussed the mechanism of uptake of both complexes as well as diagnostic and therapeutic application in a clinical scenario.
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spelling pubmed-45796122015-10-01 Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy Shukla, Jaya Mittal, Bhagwant Rai Indian J Nucl Med Review Article Dimercaptosuccinic acid (DMSA) is an analog of dimercaprol used as metal chelating moiety in variety of conditions. In nuclear medicine itself two types of Tc-99m DMSA complexes are used, trivalent and pentavalent forms. In this review, we have discussed the mechanism of uptake of both complexes as well as diagnostic and therapeutic application in a clinical scenario. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4579612/ /pubmed/26430311 http://dx.doi.org/10.4103/0972-3919.164015 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms
spellingShingle Review Article
Shukla, Jaya
Mittal, Bhagwant Rai
Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy
title Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy
title_full Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy
title_fullStr Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy
title_full_unstemmed Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy
title_short Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy
title_sort dimercaptosuccinic acid: a multifunctional cost effective agent for imaging and therapy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579612/
https://www.ncbi.nlm.nih.gov/pubmed/26430311
http://dx.doi.org/10.4103/0972-3919.164015
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