Cargando…

Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A(2) to Modulate Inflammation and Fever

BACKGROUND: Matrix metalloproteinase (MMP)‐2 deficiency makes humans and mice susceptible to inflammation. Here, we reveal an MMP‐2–mediated mechanism that modulates the inflammatory response via secretory phospholipase A(2) (sPLA(2)), a phospholipid hydrolase that releases fatty acids, including pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Berry, Evan, Hernandez‐Anzaldo, Samuel, Ghomashchi, Farideh, Lehner, Richard, Murakami, Makoto, Gelb, Michael H., Kassiri, Zamaneh, Wang, Xiang, Fernandez‐Patron, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579961/ https://www.ncbi.nlm.nih.gov/pubmed/25820137 http://dx.doi.org/10.1161/JAHA.115.001868

Ejemplares similares

Identification of a Novel Heart–Liver Axis: Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A(2) to Modulate Lipid Metabolism and Inflammation in the Liver
por: Hernandez‐Anzaldo, Samuel, et al.
Publicado: (2015)

Novel Role for Matrix Metalloproteinase 9 in Modulation of Cholesterol Metabolism
por: Hernandez‐Anzaldo, Samuel, et al.
Publicado: (2016)

Absence of Tissue Inhibitor of Metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption
por: Sakamuri, Siva S. V. P., et al.
Publicado: (2017)

Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology
por: Fan, Dong, et al.
Publicado: (2020)

Metabolic regulation by secreted phospholipase A(2)
por: Sato, Hiroyasu, et al.
Publicado: (2016)

Integrated Lipidomics in the Secreted Phospholipase A(2) Biology
por: Murakami, Makoto, et al.
Publicado: (2011)

The role of group IIF-secreted phospholipase A(2) in epidermal homeostasis and hyperplasia
por: Yamamoto, Kei, et al.
Publicado: (2015)

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm
por: Jana, Sayantan, et al.
Publicado: (2019)

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease
por: Fan, Dong, et al.
Publicado: (2012)

Secreted phospholipase A(2), lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics
por: Yamamoto, Kei, et al.
Publicado: (2011)

Group IID, IIE, IIF and III secreted phospholipase A(2)s()
por: Murakami, Makoto, et al.
Publicado: (2019)

A novel anti-inflammatory role for secretory phospholipase A(2) in immune complex-mediated arthritis
por: Boilard, Eric, et al.
Publicado: (2010)

The interaction of secreted phospholipase A(2)-IIA with the microbiota alters its lipidome and promotes inflammation
por: Doré, Etienne, et al.
Publicado: (2022)

Matrix Metalloproteinases in Health and Disease in the Times of COVID-19
por: Fernandez-Patron, Carlos, et al.
Publicado: (2022)

Group III secreted phospholipase A(2) transgenic mice spontaneously develop inflammation
por: Sato, Hiroyasu, et al.
Publicado: (2009)

Modulation of Cardiac Fibrosis in and Beyond Cells
por: Fan, Dong, et al.
Publicado: (2021)

Lipoquality control by phospholipase A(2) enzymes
por: MURAKAMI, Makoto
Publicado: (2017)

The Roles of the Secreted Phospholipase A(2) Gene Family in Immunology
por: Murakami, M., et al.
Publicado: (2016)

Destroy to Rebuild: The Connection Between Bone Tissue Remodeling and Matrix Metalloproteinases
por: Hardy, Eugenio, et al.
Publicado: (2020)

ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)–Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm
por: Jana, Sayantan, et al.
Publicado: (2020)

Updating Phospholipase A(2) Biology
por: Murakami, Makoto, et al.
Publicado: (2020)

Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice
por: Fukushima, Kenji, et al.
Publicado: (2021)

Critical role of phospholipase A(2) group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection
por: Vijay, Rahul, et al.
Publicado: (2015)

Group IIA secreted phospholipase A(2) controls skin carcinogenesis and psoriasis by shaping the gut microbiota
por: Miki, Yoshimi, et al.
Publicado: (2022)

Key Role of Group V Secreted Phospholipase A(2) in Th2 Cytokine and Dendritic Cell-Driven Airway Hyperresponsiveness and Remodeling
por: Henderson Jr, William R., et al.
Publicado: (2013)

Mast Cell-Specific Deletion of Group III Secreted Phospholipase A(2) Impairs Mast Cell Maturation and Functions
por: Taketomi, Yoshitaka, et al.
Publicado: (2021)

Secreted Phospholipases A(2) - not just Enzymes: Revisited
por: Ivanušec, Adrijan, et al.
Publicado: (2022)

Video-Rate Bioluminescence Imaging of Matrix Metalloproteinase-2 Secreted from a Migrating Cell
por: Suzuki, Takahiro, et al.
Publicado: (2011)

The Non-Fibrillar Side of Fibrosis: Contribution of the Basement Membrane, Proteoglycans, and Glycoproteins to Myocardial Fibrosis
por: Chute, Michael, et al.
Publicado: (2019)

Methods for Analysis of Matrix Metalloproteinase Regulation of Neutrophil-Endothelial Cell Adhesion
por: Fernandez-Patron, Carlos, et al.
Publicado: (2002)

Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts
por: Jana, Sayantan, et al.
Publicado: (2018)

Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
por: Hur, J. H., et al.
Publicado: (2000)

Interplay between Matrix Metalloproteinase-9, Matrix Metalloproteinase-2, and Interleukins in Multiple Sclerosis Patients
por: Trentini, Alessandro, et al.
Publicado: (2016)

Assay of phospholipases A(2) and their inhibitors by kinetic analysis in the scooting mode
por: Jain, Mahendra Kumar, et al.
Publicado: (1992)

The Repression of Matrix Metalloproteinases and Cytokine Secretion in Glioblastoma by Targeting K+ Channel
por: Saadat, Farshid, et al.
Publicado: (2021)

WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
por: Sneeggen, Marte, et al.
Publicado: (2019)

Regulatory Roles of Phospholipase A(2) Enzymes and Bioactive Lipids in Mast Cell Biology
por: Taketomi, Yoshitaka, et al.
Publicado: (2022)

Elevated Expression of Matrix Metalloproteinase-9 not Matrix Metalloproteinase-2 Contributes to Progression of Extracranial Arteriovenous Malformation
por: Wei, Ting, et al.
Publicado: (2016)

Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
por: Kang, Dong-Geun, et al.
Publicado: (2017)

Study of Matrix Metalloproteinase-2 in Inguinal Hernia
por: Jain, Vinod, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_7o3nee1kh6t9hq2r9fc6i2ok6p