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BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells
BACKGROUND: MicroRNA-200 (miR-200) suppresses the epithelial-mesenchymal transition of various cancer cells, including lung adenocarcinoma cells. We found that bone morphogenetic protein 4 (BMP4) was decreased in miR-200-overexpressing cells and epithelial-like lung cancer cells. In this study, we i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580148/ https://www.ncbi.nlm.nih.gov/pubmed/26395571 http://dx.doi.org/10.1186/s12943-015-0441-y |