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Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis

Viral myocarditis, which is most prevalently caused by coxsackievirus B3 (CVB3), is a serious clinical condition characterized by excessive myocardial inflammation. Recent studies suggest that regulation of protein acetylation levels by inhibiting histone deacetylase (HDAC) activity modulates inflam...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, He, Xiran, Gao, Bo, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580191/
https://www.ncbi.nlm.nih.gov/pubmed/26269170
http://dx.doi.org/10.1128/JVI.01028-15

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