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The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases

The telomere is present at the ends of all eukaryotic chromosomes and usually consists of repetitive TG-rich DNA that terminates in a single-stranded 3′ TG extension and a 5′ CA-rich recessed strand. A biochemical assay that allows the in vitro observation of exonuclease-catalyzed degradation (resec...

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Detalles Bibliográficos
Autores principales:	Greetham, Matthew, Skordalakes, Emmanuel, Lydall, David, Connolly, Bernard A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580210/ https://www.ncbi.nlm.nih.gov/pubmed/26264873 http://dx.doi.org/10.1016/j.jmb.2015.08.002

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