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Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study
BACKGROUND: It is known that intra-abdominal hypertension has high morbidity in acute pancreatitis and has detrimental effects on patients. For third trimester pregnancy complicated by acute pancreatitis, the intra-abdominal pressure may have its own characteristic. This article will discuss this cl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580263/ https://www.ncbi.nlm.nih.gov/pubmed/26394674 http://dx.doi.org/10.1186/s12884-015-0651-8 |
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author | Sun, Liqun Li, Weiqin Sun, Fuxi Geng, Yanxia Tong, Zhihui Li, Jieshou |
author_facet | Sun, Liqun Li, Weiqin Sun, Fuxi Geng, Yanxia Tong, Zhihui Li, Jieshou |
author_sort | Sun, Liqun |
collection | PubMed |
description | BACKGROUND: It is known that intra-abdominal hypertension has high morbidity in acute pancreatitis and has detrimental effects on patients. For third trimester pregnancy complicated by acute pancreatitis, the intra-abdominal pressure may have its own characteristic. This article will discuss this clinical scenario. METHODS: This observational study in a cohort group was performed in the surgical intensive care unit of a tertiary hospital. Medical records were reviewed from each acute pancreatitis exactly in third trimester pregnancy. The main statistical methods were Mann–Whitney U test and bivariate Pearson correlation analysis. RESULTS: During the study interval, there were totally 17 pregnancies complicated by acute pancreatitis in the third trimester. All cases with moderate or severe acute pancreatitis had intra-abdominal hypertension of mean value of 16.7 mm Hg (range, 12.9–22.0 mm Hg). The intra-abdominal pressure had significant correlation with APACHE II score (r = 0.7456, p = 0.0006), while a negative correlation was showed with the umbilical artery pH value and with 1-min Apgar score (r = −0.8232, p = 0.0005; r = −0.7465, p = 0.0034; respectively). The intra-abdominal pressure of those with live infants was lower than that of those with dead ones (13.78 ± 2.554 vs. 19.84 ± 1.695, p = 0.0019). CONCLUSIONS: The incidence of intra-abdominal hypertension seems higher in moderate or severe acute pancreatitis in third trimester pregnancy than the non-pregnant cases but there’s no significance in this study. Acute elevated intra-abdominal pressure accounts for great association with mother’s serious scenario and fetal mortality. |
format | Online Article Text |
id | pubmed-4580263 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45802632015-09-24 Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study Sun, Liqun Li, Weiqin Sun, Fuxi Geng, Yanxia Tong, Zhihui Li, Jieshou BMC Pregnancy Childbirth Research Article BACKGROUND: It is known that intra-abdominal hypertension has high morbidity in acute pancreatitis and has detrimental effects on patients. For third trimester pregnancy complicated by acute pancreatitis, the intra-abdominal pressure may have its own characteristic. This article will discuss this clinical scenario. METHODS: This observational study in a cohort group was performed in the surgical intensive care unit of a tertiary hospital. Medical records were reviewed from each acute pancreatitis exactly in third trimester pregnancy. The main statistical methods were Mann–Whitney U test and bivariate Pearson correlation analysis. RESULTS: During the study interval, there were totally 17 pregnancies complicated by acute pancreatitis in the third trimester. All cases with moderate or severe acute pancreatitis had intra-abdominal hypertension of mean value of 16.7 mm Hg (range, 12.9–22.0 mm Hg). The intra-abdominal pressure had significant correlation with APACHE II score (r = 0.7456, p = 0.0006), while a negative correlation was showed with the umbilical artery pH value and with 1-min Apgar score (r = −0.8232, p = 0.0005; r = −0.7465, p = 0.0034; respectively). The intra-abdominal pressure of those with live infants was lower than that of those with dead ones (13.78 ± 2.554 vs. 19.84 ± 1.695, p = 0.0019). CONCLUSIONS: The incidence of intra-abdominal hypertension seems higher in moderate or severe acute pancreatitis in third trimester pregnancy than the non-pregnant cases but there’s no significance in this study. Acute elevated intra-abdominal pressure accounts for great association with mother’s serious scenario and fetal mortality. BioMed Central 2015-09-22 /pmc/articles/PMC4580263/ /pubmed/26394674 http://dx.doi.org/10.1186/s12884-015-0651-8 Text en © Sun et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Sun, Liqun Li, Weiqin Sun, Fuxi Geng, Yanxia Tong, Zhihui Li, Jieshou Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
title | Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
title_full | Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
title_fullStr | Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
title_full_unstemmed | Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
title_short | Intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
title_sort | intra-abdominal pressure in third trimester pregnancy complicated by acute pancreatitis: an observational study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580263/ https://www.ncbi.nlm.nih.gov/pubmed/26394674 http://dx.doi.org/10.1186/s12884-015-0651-8 |
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