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Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response

Cancer stem cells (CSCs) possess capacity to both self-renew and generate all cells within a tumor, and are thought to drive tumor recurrence. Targeting the stem cell niche to eradicate CSCs represents an important area of therapeutic development. The complex nature of many interacting elements of t...

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Detalles Bibliográficos
Autores principales:	Sehl, Mary E., Shimada, Miki, Landeros, Alfonso, Lange, Kenneth, Wicha, Max S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580445/ https://www.ncbi.nlm.nih.gov/pubmed/26397099 http://dx.doi.org/10.1371/journal.pone.0135797

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