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Designing and Implementing an Assay for the Detection of Rare and Divergent NRPS and PKS Clones in European, Antarctic and Cuban Soils

The ever increasing microbial resistome means there is an urgent need for new antibiotics. Metagenomics is an underexploited tool in the field of drug discovery. In this study we aimed to produce a new updated assay for the discovery of biosynthetic gene clusters encoding bioactive secondary metabol...

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Detalles Bibliográficos
Autores principales:	Amos, Gregory C. A., Borsetto, Chiara, Laskaris, Paris, Krsek, Martin, Berry, Andrew E., Newsham, Kevin K., Calvo-Bado, Leo, Pearce, David A., Vallin, Carlos, Wellington, Elizabeth M. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580463/ https://www.ncbi.nlm.nih.gov/pubmed/26398766 http://dx.doi.org/10.1371/journal.pone.0138327

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