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Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility

Cell cycle checkpoint intervention is an effective therapeutic strategy for cancer when applied to patients predisposed to respond and the treatment is well-tolerated. A critical cell cycle process that could be targeted is the mitotic checkpoint (spindle assembly checkpoint) which governs the metap...

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Detalles Bibliográficos
Autores principales:	Martinez, Ricardo, Blasina, Alessandra, Hallin, Jill F., Hu, Wenyue, Rymer, Isha, Fan, Jeffery, Hoffman, Robert L., Murphy, Sean, Marx, Matthew, Yanochko, Gina, Trajkovic, Dusko, Dinh, Dac, Timofeevski, Sergei, Zhu, Zhou, Sun, Peiquing, Lappin, Patrick B., Murray, Brion W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580473/ https://www.ncbi.nlm.nih.gov/pubmed/26398286 http://dx.doi.org/10.1371/journal.pone.0138616

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