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YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression

Mechanisms underlying ovarian cancer initiation and progression are unclear. Herein, we report that the Yes-associated protein (YAP), a major effector of the Hippo tumor suppressor pathway, interacts with ERBB signaling pathways to regulate the initiation and progression of ovarian cancer. Immunohis...

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Detalles Bibliográficos
Autores principales: He, Chunbo, Lv, Xiangmin, Hua, Guohua, Lele, Subodh M, Remmenga, Steven, Dong, Jixin, Davis, John S, Wang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580488/
https://www.ncbi.nlm.nih.gov/pubmed/25798835
http://dx.doi.org/10.1038/onc.2015.52

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