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glpx Gene in Mycobacterium tuberculosis Is Required for In Vitro Gluconeogenic Growth and In Vivo Survival

Several enzymes involved in central carbon metabolism and gluconeogenesisplay a critical role in survival and pathogenesis of Mycobacterium tuberculosis (Mtb). The only known functional fructose 1,6-bisphosphatase (FBPase) in Mtb is encoded by the glpX gene and belongs to the Class II sub-family of...

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Detalles Bibliográficos
Autores principales:	Gutka, Hiten J., Wang, Yuehong, Franzblau, Scott G., Movahedzadeh, Farahnaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580611/ https://www.ncbi.nlm.nih.gov/pubmed/26397812 http://dx.doi.org/10.1371/journal.pone.0138436

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