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Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by selective degeneration of motor neurons. Mutant superoxide dismutase 1 (SOD1) is often found as aggregates in the cytoplasm in motor neurons of various mouse models and familial ALS patients. The interplay between...

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Detalles Bibliográficos
Autores principales:	Lee, Do-Yeon, Jeon, Gye Sun, Shim, Yu-mi, Seong, Seung-Yong, Lee, Kwang-Woo, Sung, Jung-Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Brain and Neural Science 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580750/ https://www.ncbi.nlm.nih.gov/pubmed/26412972 http://dx.doi.org/10.5607/en.2015.24.3.226

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