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Discrete partitioning of HIV-1 Env forms revealed by viral capture

BACKGROUND: The structure of HIV-1 envelope glycoprotein (Env) is flexible and heterogeneous on whole virions. Although functional Env complexes are thought to require trimerization of cleaved gp41/gp120 heterodimers, variable processing can result in the potential incorporation of non-functional un...

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Detalles Bibliográficos
Autores principales: Stieh, Daniel J., King, Deborah F., Klein, Katja, Aldon, Yoann, McKay, Paul F., Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581120/
https://www.ncbi.nlm.nih.gov/pubmed/26399966
http://dx.doi.org/10.1186/s12977-015-0207-z

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