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Validation of FRET Assay for the Screening of Growth Inhibitors of Escherichia coli Reveals Elongasome Assembly Dynamics

The increase in antibiotic resistant bacteria demands the development of new antibiotics against preferably new targets. The common approach is to test compounds for their ability to kill bacteria or to design molecules that inhibit essential protein activities in vitro. In the first case, the mode...

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Detalles Bibliográficos
Autores principales: van der Ploeg, René, Goudelis, Spyridon Theodoros, den Blaauwen, Tanneke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581212/
https://www.ncbi.nlm.nih.gov/pubmed/26263980
http://dx.doi.org/10.3390/ijms160817637