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A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA)

Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder and the leading genetic cause of death in infants. Despite the disease-causing gene, survival motor neuron (SMN1), encodes a ubiquitous protein, SMN1 deficiency preferentially affects spinal motor neurons (MNs), leaving the basis o...

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Detalles Bibliográficos
Autores principales: Luchetti, Andrea, Ciafrè, Silvia Anna, Murdocca, Michela, Malgieri, Arianna, Masotti, Andrea, Sanchez, Massimo, Farace, Maria Giulia, Novelli, Giuseppe, Sangiuolo, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581247/
https://www.ncbi.nlm.nih.gov/pubmed/26258776
http://dx.doi.org/10.3390/ijms160818312