Cargando…

Overview of Nrf2 as Therapeutic Target in Epilepsy

Oxidative stress is a biochemical state of imbalance in the production of reactive oxygen and nitrogen species and antioxidant defenses. It is involved in the physiopathology of degenerative and chronic neuronal disorders, such as epilepsy. Experimental evidence in humans and animals support the inv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carmona-Aparicio, Liliana, Pérez-Cruz, Claudia, Zavala-Tecuapetla, Cecilia, Granados-Rojas, Leticia, Rivera-Espinosa, Liliana, Montesinos-Correa, Hortencia, Hernández-Damián, Jacqueline, Pedraza-Chaverri, José, Sampieri, Aristides III, Coballase-Urrutia, Elvia, Cárdenas-Rodríguez, Noemí
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581249/ https://www.ncbi.nlm.nih.gov/pubmed/26262608 http://dx.doi.org/10.3390/ijms160818348

Ejemplares similares

Relevance of the Glutathione System in Temporal Lobe Epilepsy: Evidence in Human and Experimental Models
por: Cárdenas-Rodríguez, Noemí, et al.
Publicado: (2014)

Protective Effect of Tilia americana var. mexicana Against Kainic Acid-induced Damage in Brain, Liver, and Kidney: Behavioral and Biochemical Changes
por: Coballase-Urrutia, Elvia, et al.
Publicado: (2022)

Modulation of Antioxidant Enzymatic Activities by Certain Antiepileptic Drugs (Valproic Acid, Oxcarbazepine, and Topiramate): Evidence in Humans and Experimental Models
por: Cárdenas-Rodríguez, Noemí, et al.
Publicado: (2013)

Role of Oxidative Stress in Refractory Epilepsy: Evidence in Patients and Experimental Models
por: Cardenas-Rodriguez, Noemi, et al.
Publicado: (2013)

Contributions of Microdialysis to New Alternative Therapeutics for Hepatic Encephalopathy
por: Rivera-Espinosa, Liliana, et al.
Publicado: (2013)

Biochemical and molecular modulation of CCl(4)-induced peripheral and central damage by Tilia americana var. mexicanaextracts
por: Coballase-Urrutia, Elvia, et al.
Publicado: (2017)

Caenorhabditis elegans: A Useful Model for Studying Metabolic Disorders in Which Oxidative Stress Is a Contributing Factor
por: Moreno-Arriola, Elizabeth, et al.
Publicado: (2014)

Anticonvulsant and Antioxidant Effects of Tilia americana var. mexicana and Flavonoids Constituents in the Pentylenetetrazole-Induced Seizures
por: Cárdenas-Rodríguez, Noemí, et al.
Publicado: (2014)

Dose-Dependent Behavioral and Antioxidant Effects of Quercetin and Methanolic and Acetonic Extracts from Heterotheca inuloides on Several Rat Tissues following Kainic Acid-Induced Status Epilepticus
por: Carmona-Aparicio, Liliana, et al.
Publicado: (2019)

Acetonic and Methanolic Extracts of Heterotheca inuloides, and Quercetin, Decrease CCl(4)-Oxidative Stress in Several Rat Tissues
por: Coballase-Urrutia, Elvia, et al.
Publicado: (2013)

Baclofen in the Therapeutic of Sequele of Traumatic Brain Injury: Spasticity
por: Pérez-Arredondo, Adán, et al.
Publicado: (2016)

Ketogenic Diet Provided During Three Months Increases KCC2 Expression but Not NKCC1 in the Rat Dentate Gyrus
por: Granados-Rojas, Leticia, et al.
Publicado: (2020)

Exposure to Sub-Lethal Doses of Permethrin Is Associated with Neurotoxicity: Changes in Bioenergetics, Redox Markers, Neuroinflammation and Morphology
por: López-Aceves, Teresita Guadalupe, et al.
Publicado: (2021)

Effects of Valproate Monotherapy on the Oxidant-Antioxidant Status in Mexican Epileptic Children: A Longitudinal Study
por: Beltrán-Sarmiento, Eduardo, et al.
Publicado: (2018)

Daytime Restricted Feeding Modifies the Temporal Expression of CYP1A1 and Attenuated Damage Induced by Benzo[a]pyrene in Rat Liver When Administered before CYP1A1 Acrophase
por: Ávila-Rosales, Oscar Samuel, et al.
Publicado: (2021)

Use of Antioxidants for the Neuro-Therapeutic Management of COVID-19
por: Cárdenas-Rodríguez, Noemí, et al.
Publicado: (2021)

Genetic variations associated with pharmacoresistant epilepsy
por: Cárdenas-Rodríguez, Noemí, et al.
Publicado: (2020)

Dietary Biotin Supplementation Modifies Hepatic Morphology without Changes in Liver Toxicity Markers
por: Riverón-Negrete, Leticia, et al.
Publicado: (2016)

Antioxidant Capacity of “Mexican Arnica” Heterotheca inuloides Cass Natural Products and Some Derivatives: Their Anti-Inflammatory Evaluation and Effect on C. elegans Life Span
por: Rodríguez-Chávez, José Luis, et al.
Publicado: (2015)

Micronuclei in Bone Marrow and Liver in relation to Hepatic Metabolism and Antioxidant Response due to Coexposure to Chloroform, Dichloromethane, and Toluene in the Rat Model
por: Belmont-Díaz, Javier, et al.
Publicado: (2014)

Insights into Potential Targets for Therapeutic Intervention in Epilepsy
por: Zavala-Tecuapetla, Cecilia, et al.
Publicado: (2020)

Diurnal variation of NMDA receptor expression in the rat cerebral cortex is associated with traumatic brain injury damage
por: Estrada-Rojo, Francisco, et al.
Publicado: (2018)

Nrf2 Activation in Chronic Kidney Disease: Promises and Pitfalls
por: Aranda-Rivera, Ana Karina, et al.
Publicado: (2022)

The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation
por: Andérica-Romero, Ana Cristina, et al.
Publicado: (2016)

Genetic Variations on Redox Control in Cardiometabolic Diseases: The Role of Nrf2
por: Zazueta, Cecilia, et al.
Publicado: (2022)

Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway
por: Silva-Islas, Carlos A., et al.
Publicado: (2019)

Métodos y equipo para el control de emisión de partículas a la atmósfera /
por: Pérez Sosa, Liliana Hortencia
Publicado: (2000)

Nrf2 and Redox Status in Prediabetic and Diabetic Patients
por: Jiménez-Osorio, Angélica S., et al.
Publicado: (2014)

Alternative kynurenic acid synthesis routes studied in the rat cerebellum
por: Blanco Ayala, Tonali, et al.
Publicado: (2015)

Corrigendum to ‘The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation’ [Redox Biol. 8 (2016) 341–347]
por: Andérica-Romero, A.C., et al.
Publicado: (2016)

Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats
por: González-Reyes, Susana, et al.
Publicado: (2013)

Different gene expression profiles in subcutaneous & visceral adipose tissues from Mexican patients with obesity
por: Ronquillo, María D., et al.
Publicado: (2019)

Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels
por: León-Aparicio, Daniel, et al.
Publicado: (2019)

Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments
por: Martínez-Klimova, Elena, et al.
Publicado: (2019)

Advances and Challenges of Cannabidiol as an Anti-Seizure Strategy: Preclinical Evidence
por: Zavala-Tecuapetla, Cecilia, et al.
Publicado: (2022)

Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats
por: Tapia, Edilia, et al.
Publicado: (2012)

Intervención humanista para incrementar la autoestima en niños de educación basica, con daño psicologico ocasionado por los castigos /
por: Rocha Urrutia, Sonia Liliana
Publicado: (2000)

Eslicarbazepine, but Not Lamotrigine or Ranolazine, Shows Anticonvulsant Efficacy in Carbamazepine-Resistant Rats Developed by Window-Pentylenetetrazole Kindling
por: Zavala-Tecuapetla, Cecilia, et al.
Publicado: (2022)

Mitochondrial Redox Signaling and Oxidative Stress in Kidney Diseases
por: Aranda-Rivera, Ana Karina, et al.
Publicado: (2021)

Antioxidant Enzymes Haplotypes and Polymorphisms Associated with Obesity in Mexican Children
por: Costa-Urrutia, Paula, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_c551g0m0pl6s7k9e6l3h5hcble