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Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase
Hepatitis C virus (HCV) is an important etiological agent of severe liver diseases, including cirrhosis and hepatocellular carcinoma. The HCV genome encodes nonstructural protein 3 (NS3) helicase, which is a potential anti-HCV drug target because its enzymatic activity is essential for viral replica...
Autores principales: | Furuta, Atsushi, Tsubuki, Masayoshi, Endoh, Miduki, Miyamoto, Tatsuki, Tanaka, Junichi, Abdus Salam, Kazi, Akimitsu, Nobuyoshi, Tani, Hidenori, Yamashita, Atsuya, Moriishi, Kohji, Nakakoshi, Masamichi, Sekiguchi, Yuji, Tsuneda, Satoshi, Noda, Naohiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581254/ https://www.ncbi.nlm.nih.gov/pubmed/26262613 http://dx.doi.org/10.3390/ijms160818439 |
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