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Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase

Hepatitis C virus (HCV) is an important etiological agent of severe liver diseases, including cirrhosis and hepatocellular carcinoma. The HCV genome encodes nonstructural protein 3 (NS3) helicase, which is a potential anti-HCV drug target because its enzymatic activity is essential for viral replica...

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Detalles Bibliográficos
Autores principales: Furuta, Atsushi, Tsubuki, Masayoshi, Endoh, Miduki, Miyamoto, Tatsuki, Tanaka, Junichi, Abdus Salam, Kazi, Akimitsu, Nobuyoshi, Tani, Hidenori, Yamashita, Atsuya, Moriishi, Kohji, Nakakoshi, Masamichi, Sekiguchi, Yuji, Tsuneda, Satoshi, Noda, Naohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581254/
https://www.ncbi.nlm.nih.gov/pubmed/26262613
http://dx.doi.org/10.3390/ijms160818439

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