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Cdc42-Interacting Protein 4 Represses E-Cadherin Expression by Promoting β-Catenin Translocation to the Nucleus in Murine Renal Tubular Epithelial Cells
Renal fibrosis is an inevitable outcome of end-stage chronic kidney disease. During this process, epithelial cells lose E-cadherin expression. β-Catenin may act as a mediator by accumulation and translocation to the nucleus. Studies have suggested that CIP4, a Cdc42 effector protein, is associated w...
Autores principales: | Xu, Chuou, Zhou, Qiaodan, Liu, Lili, Liu, Ping, Pei, Guangchang, Zeng, Rui, Han, Min, Xu, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581292/ https://www.ncbi.nlm.nih.gov/pubmed/26287173 http://dx.doi.org/10.3390/ijms160819170 |
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