Cargando…

15,16-Dihydrotanshinone I from the Functional Food Salvia miltiorrhiza Exhibits Anticancer Activity in Human HL-60 Leukemia Cells: in Vitro and in Vivo Studies

15,16-Dihydrotanshinone I (DHTS) is extracted from Salvia miltiorrhiza Bunge which is a functional food in Asia. In this study, we investigated the apoptotic effect of DHTS on the human acute myeloid leukemia (AML) type III HL-60 cell line. We found that treatment with 1.5 μg/mL DHTS increased proap...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jun-Jen, Wu, Hsueh-Hsia, Chen, Tzu-Ho, Leung, Wan, Liang, Yu-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581302/ https://www.ncbi.nlm.nih.gov/pubmed/26287183 http://dx.doi.org/10.3390/ijms160819387

Ejemplares similares

15,16-Dihydrotanshinone I, a Compound of Salvia miltiorrhiza Bunge, Induces Apoptosis through Inducing Endoplasmic Reticular Stress in Human Prostate Carcinoma Cells
por: Chuang, Mao-Te, et al.
Publicado: (2011)

15,16-dihydrotanshinone I inhibits EOMA cells proliferation by interfering in posttranscriptional processing of hypoxia-inducible factor 1
por: Duan, Peiwen, et al.
Publicado: (2021)

Chromosome Doubling-Enhanced Biomass and Dihydrotanshinone I Production in Salvia miltiorrhiza, A Traditional Chinese Medicinal Plant
por: Chen, Elena Gamboa, et al.
Publicado: (2018)

Chromosome-level genome assembly of Salvia miltiorrhiza with orange roots uncovers the role of Sm2OGD3 in catalyzing 15,16-dehydrogenation of tanshinones
por: Pan, Xian, et al.
Publicado: (2023)

Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation
por: Gao, Hongwei, et al.
Publicado: (2018)

ent-(15S)-Pimar-8(14)-ene-15,16-diol
por: Fun, Hoong-Kun, et al.
Publicado: (2012)

Roles of Reactive Oxygen Species in Anticancer Therapy with Salvia miltiorrhiza Bunge
por: Hung, Yu-Chiang, et al.
Publicado: (2016)

Anticancer Effects of Salvia miltiorrhiza Alcohol Extract on Oral Squamous Carcinoma Cells
por: Wang, Wen-Hung, et al.
Publicado: (2017)

Subcritical Water Extraction of Salvia miltiorrhiza
por: Kapalavavi, Brahmam, et al.
Publicado: (2021)

Corrigendum to “Anticancer Effects of Salvia miltiorrhiza Alcohol Extract on Oral Squamous Carcinoma Cells”
por: Wang, Wen-Hung, et al.
Publicado: (2017)

Anti-proliferative Effect of 15,16-Dihydrotanshinone I Through Cell Cycle Arrest and the Regulation of AMP-activated Protein Kinase/Akt/mTOR and Mitogen-activated Protein Kinase Signaling Pathway in Human Hepatocellular Carcinoma Cells
por: Hong, Ji-Young, et al.
Publicado: (2018)

The carcinogenicity of 15,16-dihydro-11-methyl-cyclopenta[a]phenanthren-17-one.
por: Coombs, M. M., et al.
Publicado: (1979)

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza
por: Jiang, Zhouqian, et al.
Publicado: (2019)

Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza
por: Li, Bin, et al.
Publicado: (2017)

Effects of Salvia miltiorrhiza extract on lung adenocarcinoma
por: Tian, Huixiang, et al.
Publicado: (2021)

Treatment of Urolithiasis with Medicinal Plant Salvia miltiorrhiza: A Nationwide Cohort Study
por: Chen, Wen-Chi, et al.
Publicado: (2018)

The autophagic inhibition oral squamous cell carcinoma cancer growth of 16-hydroxy-cleroda-3,14-dine-15,16-olide
por: Cheng, Ming-Fang, et al.
Publicado: (2017)

Antihypertension Induced by Tanshinone IIA Isolated from the Roots of Salvia miltiorrhiza
por: Chan, Paul, et al.
Publicado: (2011)

SmbHLH60 and SmMYC2 antagonistically regulate phenolic acids and anthocyanins biosynthesis in Salvia miltiorrhiza
por: Liu, Shucan, et al.
Publicado: (2022)

Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction
por: Lin, Tsai-Hui, et al.
Publicado: (2010)

Transcriptome Sequencing in Response to Salicylic Acid in Salvia miltiorrhiza
por: Zhang, Xiaoru, et al.
Publicado: (2016)

The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza
por: Ma, Xiao-Hui, et al.
Publicado: (2015)

Effects of cadmium on the synthesis of active ingredients in Salvia miltiorrhiza
por: Fu, Haihui, et al.
Publicado: (2023)

Mechanism modeling and application of Salvia miltiorrhiza percolation process
por: Wang, Wanying, et al.
Publicado: (2023)

Overexpression of SmANS Enhances Anthocyanin Accumulation and Alters Phenolic Acids Content in Salvia miltiorrhiza and Salvia miltiorrhiza Bge f. alba Plantlets
por: Li, Hongyan, et al.
Publicado: (2019)

Protocatechuic aldehyde from Salvia miltiorrhiza exhibits an anti-inflammatory effect through inhibiting MAPK signalling pathway
por: Wu, Shuang, et al.
Publicado: (2020)

15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo
por: Cai, Yihong, et al.
Publicado: (2018)

Characterization of Salvia Miltiorrhiza ethanol extract as an anti-osteoporotic agent
por: Cui, Yan, et al.
Publicado: (2011)

The Complete Chloroplast Genome Sequence of the Medicinal Plant Salvia miltiorrhiza
por: Qian, Jun, et al.
Publicado: (2013)

Immunomodulatory Effects of Danshen (Salvia miltiorrhiza) in BALB/c Mice
por: Gao, Donghong, et al.
Publicado: (2012)

Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza
por: Gao, Wei, et al.
Publicado: (2014)

A Dominant Gene for Male Sterility in Salvia miltiorrhiza Bunge
por: Shu, Zhiming, et al.
Publicado: (2012)

Oxidative Stress and Salvia miltiorrhiza in Aging-Associated Cardiovascular Diseases
por: Chang, Cheng-Chieh, et al.
Publicado: (2016)

Molecular Mechanism of Salvia miltiorrhiza Bunge in Treating Cerebral Infarction
por: Ye, Xietao, et al.
Publicado: (2022)

Salvia miltiorrhiza Bunge (Danshen) for Treatment and Prevention of Urolithiasis: A Drosophila Animal Study
por: Chen, Wen-Chi, et al.
Publicado: (2019)

Effects of Salvia miltiorrhiza ethanolic extract on lipopolysaccharide-induced dental alveolar bone resorption in rats
por: Tsai, Huang-Tzu, et al.
Publicado: (2016)

16-Hydroxycleroda-3,13-dien-15,16-olide and N-Methyl-Actinodaphine Potentiate Tamoxifen-Induced Cell Death in Breast Cancer
por: Velmurugan, Bharath Kumar, et al.
Publicado: (2018)

Retraction Note: Protocatechuic aldehyde from Salvia miltiorrhiza exhibits an anti-inflammatory effect through inhibiting MAPK signalling pathway
por: Wu, Shuang, et al.
Publicado: (2023)

Treating oligohydramnios with extract of Salvia miltiorrhiza: A randomized control trial
por: Chu, Hong-nü, et al.
Publicado: (2008)

Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions
por: Adams, James David, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_f5cllqvbh2gssiero1hddf3j8r