Over-Expression of Porcine Myostatin Missense Mutant Leads to A Gender Difference in Skeletal Muscle Growth between Transgenic Male and Female Mice

Myostatin, a transforming growth factor-β family member, is a negative regulator of skeletal muscle development and growth. Piedmontese cattle breeds have a missense mutation, which results in a cysteine to tyrosine substitution in the mature myostatin protein (C313Y). This loss-of-function mutation...

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Detalles Bibliográficos
Autores principales: Ma, Dezun, Gao, Pengfei, Qian, Lili, Wang, Qingqing, Cai, Chunbo, Jiang, Shengwang, Xiao, Gaojun, Cui, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581338/
https://www.ncbi.nlm.nih.gov/pubmed/26305245
http://dx.doi.org/10.3390/ijms160820020

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