Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations

RNA polymerase (RNAP) performs various tasks during transcription by changing its conformational states, which are gradually becoming clarified. A recent study focusing on the conformational transition of RNAP between the ratcheted and tight forms illuminated the structural principles underlying its...

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Detalles Bibliográficos
Autores principales: Sekine, Shun-ichi, Murayama, Yuko, Svetlov, Vladimir, Nudler, Evgeny, Yokoyama, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581356/
https://www.ncbi.nlm.nih.gov/pubmed/26226152
http://dx.doi.org/10.1080/21541264.2015.1059922
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author Sekine, Shun-ichi
Murayama, Yuko
Svetlov, Vladimir
Nudler, Evgeny
Yokoyama, Shigeyuki
author_facet Sekine, Shun-ichi
Murayama, Yuko
Svetlov, Vladimir
Nudler, Evgeny
Yokoyama, Shigeyuki
author_sort Sekine, Shun-ichi
collection PubMed
description RNA polymerase (RNAP) performs various tasks during transcription by changing its conformational states, which are gradually becoming clarified. A recent study focusing on the conformational transition of RNAP between the ratcheted and tight forms illuminated the structural principles underlying its functional operations.
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spelling pubmed-45813562016-02-03 Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations Sekine, Shun-ichi Murayama, Yuko Svetlov, Vladimir Nudler, Evgeny Yokoyama, Shigeyuki Transcription Point-of-View RNA polymerase (RNAP) performs various tasks during transcription by changing its conformational states, which are gradually becoming clarified. A recent study focusing on the conformational transition of RNAP between the ratcheted and tight forms illuminated the structural principles underlying its functional operations. Taylor & Francis 2015-07-30 /pmc/articles/PMC4581356/ /pubmed/26226152 http://dx.doi.org/10.1080/21541264.2015.1059922 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Point-of-View
Sekine, Shun-ichi
Murayama, Yuko
Svetlov, Vladimir
Nudler, Evgeny
Yokoyama, Shigeyuki
Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations
title Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations
title_full Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations
title_fullStr Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations
title_full_unstemmed Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations
title_short Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations
title_sort ratcheting of rna polymerase toward structural principles of rna polymerase operations
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581356/
https://www.ncbi.nlm.nih.gov/pubmed/26226152
http://dx.doi.org/10.1080/21541264.2015.1059922
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