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Characterizing of Four Common BCR-ABL Kinase Domain Mutations (T315I, Y253H, M351T and E255K) in Iranian Chronic Myelogenous Leukemia Patients With Imatinib Resistance

BACKGROUND: Chronic myelogenous leukemia (CML) is a kind of hematopoietic stem-cell cancer. A significant number of CML patients who do not achieve an acceptable response to therapy, show acquired resistance against Imatinib. One of the most considerable causes of resistance against Imatinib as the...

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Detalles Bibliográficos
Autores principales:	Rejali, Leili, Poopak, Behzad, Hasanzad, Mandana, Sheikhsofla, Fatemeh, Varnoosfaderani, Ameneh Saadat, Safari, Nazila, Rabieipoor, Saghar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shahid Beheshti University of Medical Sciences 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581365/ https://www.ncbi.nlm.nih.gov/pubmed/26413254 http://dx.doi.org/10.17795/ijcp2334

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