Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome

We report a case of a 37-year-old woman presenting with dysphagia and thyroid masses who was subsequently diagnosed with Lhermitte-Duclos disease (LDD) based on MRI scan and histopathology. Additional imaging subsequently revealed the presence of thyroid nodules and bilateral breast cancers. Genetic...

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Detalles Bibliográficos
Autores principales: Hu, Zishuo Ian, Bangiyev, Lev, Seidman, Roberta J., Cohen, Jules A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581503/
https://www.ncbi.nlm.nih.gov/pubmed/26448889
http://dx.doi.org/10.1155/2015/546297
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author Hu, Zishuo Ian
Bangiyev, Lev
Seidman, Roberta J.
Cohen, Jules A.
author_facet Hu, Zishuo Ian
Bangiyev, Lev
Seidman, Roberta J.
Cohen, Jules A.
author_sort Hu, Zishuo Ian
collection PubMed
description We report a case of a 37-year-old woman presenting with dysphagia and thyroid masses who was subsequently diagnosed with Lhermitte-Duclos disease (LDD) based on MRI scan and histopathology. Additional imaging subsequently revealed the presence of thyroid nodules and bilateral breast cancers. Genetic testing later confirmed the diagnosis of Cowden syndrome. This case illustrates the importance of the overlap between LDD, Cowden syndrome, thyroid disease, and breast cancer.
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spelling pubmed-45815032015-10-07 Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome Hu, Zishuo Ian Bangiyev, Lev Seidman, Roberta J. Cohen, Jules A. Case Rep Oncol Med Case Report We report a case of a 37-year-old woman presenting with dysphagia and thyroid masses who was subsequently diagnosed with Lhermitte-Duclos disease (LDD) based on MRI scan and histopathology. Additional imaging subsequently revealed the presence of thyroid nodules and bilateral breast cancers. Genetic testing later confirmed the diagnosis of Cowden syndrome. This case illustrates the importance of the overlap between LDD, Cowden syndrome, thyroid disease, and breast cancer. Hindawi Publishing Corporation 2015 2015-09-10 /pmc/articles/PMC4581503/ /pubmed/26448889 http://dx.doi.org/10.1155/2015/546297 Text en Copyright © 2015 Zishuo Ian Hu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hu, Zishuo Ian
Bangiyev, Lev
Seidman, Roberta J.
Cohen, Jules A.
Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome
title Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome
title_full Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome
title_fullStr Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome
title_full_unstemmed Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome
title_short Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome
title_sort dysphagia and neck swelling in a case of undiagnosed lhermitte-duclos disease and cowden syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581503/
https://www.ncbi.nlm.nih.gov/pubmed/26448889
http://dx.doi.org/10.1155/2015/546297
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