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Selective Activation of Cancer Stem Cells by Size-Specific Hyaluronan in Head and Neck Cancer

We determined that human head and neck cancer cells (HSC-3 cell line) contain a subpopulation displaying cancer stem cell (CSC) properties and are very tumorigenic. Specifically, we investigated whether different sizes of hyaluronan (HA) (e.g., 5 kDa, 20 kDa, 200 kDa, or 700 kDa-HA-sizes) play a rol...

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Detalles Bibliográficos
Autores principales: Shiina, Marisa, Bourguignon, Lilly Y. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581563/
https://www.ncbi.nlm.nih.gov/pubmed/26448762
http://dx.doi.org/10.1155/2015/989070