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Urine Stasis Predisposes to Urinary Tract Infection by an Opportunistic Uropathogen in the Megabladder (Mgb) Mouse

PURPOSE: Urinary stasis is a risk factor for recurrent urinary tract infection (UTI). Homozygous mutant Megabladder (Mgb-/-) mice exhibit incomplete bladder emptying as a consequence of congenital detrusor aplasia. We hypothesize that this predisposes Mgb-/- mice to spontaneous and experimental UTI....

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Detalles Bibliográficos
Autores principales:	Becknell, Brian, Mohamed, Ahmad Z., Li, Birong, Wilhide, Michael E., Ingraham, Susan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581623/ https://www.ncbi.nlm.nih.gov/pubmed/26401845 http://dx.doi.org/10.1371/journal.pone.0139077

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