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Aberrant Wnt/β-catenin signaling and elevated expression of stem cell proteins are associated with osteosarcoma side population cells of high tumorigenicity

According to the cancer stem cell theory, the presence of a small sub-population of cancer cells, termed cancer stem cells (CSCs), have a significant implication on cancer treatment and are responsible for tumor recurrence. Previous studies have reported that alterations in the Wnt/β-catenin signali...

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Detalles Bibliográficos
Autores principales: YI, XI-JUN, ZHAO, YU-HUA, QIAO, LI-XIANG, JIN, CHUN-LEI, TIAN, JING, LI, QIU-SHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581745/
https://www.ncbi.nlm.nih.gov/pubmed/26134785
http://dx.doi.org/10.3892/mmr.2015.4025