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Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye
Dry eye is a common disorder caused by inadequate hydration of the ocular surface that results in disruption of barrier function. The homeostatic protein clusterin (CLU) is prominent at fluid-tissue interfaces throughout the body. CLU levels are reduced at the ocular surface in human inflammatory di...
Autores principales: | Bauskar, Aditi, Mack, Wendy J., Mauris, Jerome, Argüeso, Pablo, Heur, Martin, Nagel, Barbara A., Kolar, Grant R., Gleave, Martin E., Nakamura, Takahiro, Kinoshita, Shigeru, Moradian-Oldak, Janet, Panjwani, Noorjahan, Pflugfelder, Stephen C., Wilson, Mark R., Fini, M. Elizabeth, Jeong, Shinwu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581869/ https://www.ncbi.nlm.nih.gov/pubmed/26402857 http://dx.doi.org/10.1371/journal.pone.0138958 |
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