HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer

Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates the adaptation of cells to hypoxic microenvironments, for example inside solid tumours. Stabilisation of HIF1α can also occur in normoxic conditions in inflamed tissue or as a result of inactivating mutations in negative re...

Descripción completa

Detalles Bibliográficos
Autores principales: Mladenova, Dessislava N., Dahlstrom, Jane E., Tran, Phuong N., Benthani, Fahad, Bean, Elaine G., Ng, Irvin, Pangon, Laurent, Currey, Nicola, Kohonen-Corish, Maija R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582097/
https://www.ncbi.nlm.nih.gov/pubmed/26183215
http://dx.doi.org/10.1242/dmm.019000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582097/
https://www.ncbi.nlm.nih.gov/pubmed/26183215
http://dx.doi.org/10.1242/dmm.019000

Ejemplares similares