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The generation and characterization of novel Col1a1(FRT-Cre-ER-T2-FRT) and Col1a1(FRT-STOP-FRT-Cre-ER-T2) mice for sequential mutagenesis
Novel genetically engineered mouse models using the Cre-loxP or the Flp-FRT systems have generated useful reagents to manipulate the mouse genome in a temporally-regulated and tissue-specific manner. By incorporating a constitutive Cre driver line into a mouse model in which FRT-regulated genes in o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582108/ https://www.ncbi.nlm.nih.gov/pubmed/26183214 http://dx.doi.org/10.1242/dmm.021204 |