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E4-Ubiquitin ligase Ufd2 stabilizes Yap8 and modulates arsenic stress responses independent of the U-box motif

Adaptation of Saccharomyces cerevisiae cells to arsenic stress is mediated through the activation of arsenic detoxification machinery by the Yap8 transcription factor. Yap8 is targeted by the ubiquitin proteasome system for degradation under physiological conditions, yet it escapes proteolysis in ar...

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Detalles Bibliográficos
Autores principales:	Ferreira, Rita T., Menezes, Regina A., Rodrigues-Pousada, Claudina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582114/ https://www.ncbi.nlm.nih.gov/pubmed/26276098 http://dx.doi.org/10.1242/bio.010405

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