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Characterization of Cep85 – a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction
Nek2 has been implicated in centrosome disjunction at the onset of mitosis to promote bipolar spindle formation, and hyperactivation of Nek2 leads to the premature centrosome separation. Its activity, therefore, needs to be strictly regulated. In this study, we report that Cep85, an uncharacterized...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582193/ https://www.ncbi.nlm.nih.gov/pubmed/26220856 http://dx.doi.org/10.1242/jcs.171637 |