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Profiling post-translational modifications of histones in human monocyte-derived macrophages
BACKGROUND: Histones and their post-translational modifications impact cellular function by acting as key regulators in the maintenance and remodeling of chromatin, thus affecting transcription regulation either positively (activation) or negatively (repression). In this study we describe a comprehe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582717/ https://www.ncbi.nlm.nih.gov/pubmed/26412985 http://dx.doi.org/10.1186/s12953-015-0080-7 |