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Novel epitopes identified from efflux pumps of Mycobacterium tuberculosis could induce cytotoxic T lymphocyte response

Overcoming drug-resistance is one of the major challenges to control tuberculosis (TB). The up-regulation of efflux pumps is one common mechanism that leads to drug-resistance. Therefore, immunotherapy targeting these efflux pump antigens could be promising strategy to be combined with current chemo...

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Detalles Bibliográficos
Autores principales: Zhai, Ming-xia, Chen, Fei, Zhao, Yuan-yuan, Wu, Ya-hong, Li, Guo-dong, Gao, Yan-feng, Qi, Yuan-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582945/
https://www.ncbi.nlm.nih.gov/pubmed/26417538
http://dx.doi.org/10.7717/peerj.1229